Online citizen science games: opportunities for the biological sciences

December 1, 2014

Recent developments in digital technologies and the rise of the internet have created new opportunities for citizen science. One of these has been the development of online citizen science games where complex research problems have […]

Foldit: Increased Diels-Alderase activity through backbone remodeling guided by Foldit players

January 22, 2012

Computational enzyme design holds promise for the production of renewable fuels, drugs and chemicals. De novo enzyme design has generated catalysts for several reactions, but with lower catalytic efficiencies than naturally occurring enzymes. Here we […]

Games with a scientific purpose

December 28, 2011

The protein folding game Foldit shows that games are an effective way to recruit, engage and organize ordinary citizens to help solve difficult scientific problems. Modern science is filled with challenges of massive scale. From […]

Foldit: Algorithm discovery by protein folding game players

November 22, 2011

Foldit is a multiplayer online game in which players collaborate and compete to create accurate protein structure models. For specific hard problems, Foldit player solutions can in some cases outperform state-of-the-art computational methods. However, very […]

Foldit: Crystal structure of a monomeric retroviral protease solved by protein folding game players

September 18, 2011

Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, we challenged players of the protein folding game Foldit to produce accurate models of […]

Foldit: Analysis of social gameplay macros in the Foldit cookbook

June 29, 2011

As games grow in complexity, gameplay needs to provide players with powerful means of managing this complexity. One approach is to give automation tools to players. In this paper, we analyze an in-game automation tool, […]

1 2 3