publication

Microtask crowdsourcing for disease mention annotation in PubMed abstracts

August 5, 2014

Identifying concepts and relationships in biomedical text enables knowledge to be applied in computational analyses. Many biological natural language process (BioNLP) projects attempt to address this challenge, but the state of the art in BioNLP […]

Serious Games for Solving Protein Sequence Alignments – Combining Citizen Science and Gaming

April 1, 2014

A fundamental task in computational biology is the identification of similarities between multiple protein sequences, to get insight into their functional, structural and evolutionary relationships. These similarities can be revealed by aligning the sequences. This […]

Forgotten Island: Exploring Data Quality in Games With a Purpose

March 15, 2014

A key problem for crowd-sourcing systems is motivating contributions from participants and ensuring the quality of these contributions. Games have been suggested as a motivational approach to encourage contribution, but attracting participation through game play […]

Immune Attack players perform better on a test of cellular immunology and self confidence[…]

March 5, 2014

Immune Attack players perform better on a test of cellular immunology and self confidence than their classmates who play a control video game As molecular scientists, we understand the fundamentals of molecular behavior that underlie […]

The Cure: Design and Evaluation of a Crowdsourcing Game for Gene Selection for Breast Cancer Survival Prediction

February 17, 2014

Background: Molecular signatures for predicting breast cancer prognosis could greatly improve care through personalization of treatment. Computational analyses of genome-wide expression datasets have identified such signatures, but these signatures leave much to be desired in […]

Eterna: RNA design rules from a massive open laboratory

February 11, 2014

Self-assembling RNA molecules present compelling substrates for the rational interrogation and control of living systems. However, imperfect in silico models—even at the secondary structure level—hinder the design of new RNAs that function properly when synthesized. […]

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